Once again, one of the issues with the F-35 JSF is that, to a greater degree than any other fighter aircraft history, the country operating the aircraft will be unable to modify its systems to meet their needs.
It now appears that the Israeli Air Force will purchase the F-35, the number that it purchases will be highly dependent on the ability it will have to install indigenous systems, as the JSF is a remarkably closed system.
In the long run, I think that follow-on orders for the aircraft may be hindered by this, as operators, and nations becoming operators, find out the degree to which they have to jump through hoops to integrate upgrades and new systems that were routine in prior aircraft.