A study has been released showing that Prozac, does not work better than a placebo for most people.
You can find the whole paper here.
The pattern they saw from the trial results of fluoxetine (Prozac), paroxetine (Seroxat), venlafaxine (Effexor) and nefazodone (Serzone) was consistent. “Using complete data sets (including unpublished data) and a substantially larger data set of this type than has been previously reported, we find the overall effect of new-generation antidepressant medication is below recommended criteria for clinical significance,” they write.
Two more frequently prescribed antidepressants were omitted from the study because scientists were unable to obtain all the data.